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Luminal aspiration/Infusion assemblies


For research studies which involve aspiration of luminal contents, and/or delivery of tracer or test substances to the gut lumen.

General principles

  • Aqueous solutions can be delivered down lumina as small as 0.28mm, dependent on assembly length and the required rate of delivery.

  • Viscous liquids require substantially larger size channels than solutions with a viscocity similar to water.

  • The diameter of the channel required for aspiration depends also on the viscosity and volume of the material aspirated, and the size of any suspended particles.

  • Effective aspiration requires the use of methods to release any vacuum generated in the aspiration line by the mucosa causing plugging of aspiration ports.

  • Channels other than the aspiration channel can be used to release vacuum, by creating vents from these channels into the aspiration channel at strategic points.

  • Luminal aspiration/infusion assemblies can be equipped with tip weights, balloons and stiffeners to aid intubation, with methods described in Technical Note 5, Version 2, pages 70 to 74.

  • It is feasible to make aspiration/infusion assemblies from any of the Dentsleeve assemblies, and for these to combine manometry with these other functions.

  • The E63 extrusion has been designed specially for infusion studies which do not require large occlusive balloons.
    E63 Infusion Assemblies

    This extrusion, which is shown below, is designed primarily for infusion studies, being especially suitable for bio-availability studies on test pharmaceuticals.

    The overall diameter of 3mm gives excellent tolerance of prolonged deep intubation.

    The four channels can be allocated to various purposes that aid infusion studies such as

    delivery of one or more test substances at different sites

    aspiration of contents

    balloon inflation


    transmucosal potential difference recordings

    Attributes of specific layouts

    Assembly design is entirely dependent on the nature of the study. Accordingly, no suggested 'standard' designs are shown.

    Dentsleeve is happy to consider the application and to advise on assembly designs that are best suited to this.

    Accessories for aspiration assemblies

  • Balloons of various types can be supplied - see Section 4, pages 49 and 50.

  • Radio-opaque marking is possible - see Section 4, page 52.

  • Tip weights and balloons can be installed to aid passage across the pylorus and along the small and large intestine - see Section 4, pages 49 to 51 and Technical Note5, Version 2, pages 70 to 74.

    2+1+1 extrusion E63
    Lumina 0.6 mm, 0.8 mm
    and oval 1.5x1.2 mm


    Dentsleeve International Ltd


    Technical Notes